Insulin Resistance
The body stores energy more aggressively when insulin signaling is chronically disturbed.
THE CHROMOSOME
The Storm
Obesity becomes a metabolic storm when hormones, hunger, liver fat, insulin resistance and inflammation begin reinforcing one another.
Inflammatory Load
Visceral fat can influence cytokines, vascular tone and cardiometabolic strain.
Medical Staging
Large weight targets require staged treatment, monitoring and maintenance rather than random dieting.